RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
mir-155
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
Masson's trichrome staining
Target
PDE3A
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Lack of microRNA-155 ameliorates renal fibrosis by targeting PDE3A/TGF-beta1/Smad signaling in mice with obstructive nephropathy
Year
2018
Function
miR-155 attenuates renal fibrosis via inhibiting TGF-beta/smad signaling activation by targeting the upstream molecule Pde3a.